Frequently Asked Questions

Cryo-1 is a handheld cooling device that uses precise “cool-not-cold” conductive cooling through the palms. These areas have special blood vessels and nerves that regulate heat and stress. As the blood in your palms cools, it circulates through the rest of your body, lowering core temperature and reducing the buildup of heat and stress signals. This process helps you feel relief in seconds while supporting overall recovery and performance.

Ice is too cold to effectively cool the body without causing blood vessels to constrict. This slows circulation and limits heat transfer.

Cryo-1, on the other hand, applies controlled “cool‑not‑cold” cooling that keeps blood flowing, removing heat faster and more effectively.

Cryo-1 is designed for athletes, women experiencing hot flashes, outdoor enthusiasts, people attending outdoor events, kids playing sports, and anyone looking for natural stress relief. Always consult your doctor if you have medical conditions.

Most users feel results within 60–90 seconds.

Cryo-1 delivers extended use on a single charge.

• Cooling runtime: 1 to 3.5 hours depending on selected temperature
• Warming runtime: 3 to 4 hours depending on selected temperature

Designed for long sessions whether you’re cooling down after a workout, managing hot flashes, or calming the nervous system.

Cryo-1 recharges via USB-C and reaches a full charge in about 3.5 to 4 hours using a standard 5V/3A power source.

No. Cryo-1 uses built-in battery powered cooling modules - no ice, water, or prep required.

Not at all. Cryo-1 operates at 47 dB, similar to a very quiet computer fan. Most users barely notice it running.

For best results, we suggest turning Cryo-1 on a couple of minutes before you need it. We recommend setting it to maximum power - three cool lights for cooling or three warm lights for warming- and allowing it to run on its own for 1–3 minutes. This lets the device reach its optimal temperature faster than if it’s being held immediately.

That’s not to say you won’t feel relief right away when using it handheld, but pre-running ensures the coldest or warmest effect.

Each cycle runs for about 20 minutes, giving you plenty of time to enjoy a session and then turn it off before the cycle completes.

Hold Cryo-1 in your palm for 1–3 minutes between sets or intervals.

You should feel an immediate sense of coolness throughout your body, but the real benefit comes in your next effort -whether that’s a heavier lift, a sharper sprint, or a steadier performance.

This brief cooling lowers core temperature and helps reverse the buildup of heat and acidic byproducts in working muscles, restoring enzyme efficiency and contraction strength so you can perform stronger on the very next set.

Think of it like letting an engine cool down so it runs smoother and with more power on the next lap.

At the onset of a hot flash, hold Cryo-1 in your palm on maximum cool for rapid relief. You should feel a cooling sensation almost immediately as excess heat is drawn from the bloodstream, which helps blunt the intensity of the episode.

In user testing, many reported their hot flashes shortened from around ten minutes to under one minute.

For nighttime use, keeping Cryo by the bed allows quick application during night sweats, helping restore comfort and return to sleep faster.

This response is consistent with clinical research showing palm cooling significantly reduces the severity and duration of menopausal vasomotor symptoms.

Apply Cryo-1 to the side of the neck in cycles of 30–60 seconds on and 30–60 seconds off. Repeat this on–off pattern until you notice your heart rate decreasing and the stress symptoms beginning to abate.

This patterned cooling activates the vagus nerve more effectively and helps the body transition from fight-or-flight into a calmer state.

A short session with Cryo-1 can deliver benefits that last well beyond the moment of use.

For athletes, cooling the palms between sets or sprints can sharpen the very next effort and sustain performance for several minutes to several hours.

For women using Cryo-1 to stop hot flashes, a single session often ends the episode entirely and provides comfort until the next occurrence.

In this way, the relief from one use can carry through workouts, daily activities, or extended periods of calm, making each session remarkably effective.

Stanford-led research shows palm cooling can increase training volume by up to 144%, extend endurance in heat by 43%, and shorten hot flashes from 10 minutes to under 60 seconds.

Cryo-1 is generally safe for healthy users. If you have heart disease, circulatory disorders, or other medical conditions, consult your physician before use.

Cryo-1 is a non-drug alternative that may help reduce symptoms, but it should not replace prescribed treatments without your doctor’s advice.

Cooling at 50–60 °F avoids vasoconstriction, allowing continuous blood flow and faster heat transfer compared to ice.

Cryo-1 comes with a one-year limited warranty covering defects in materials and workmanship.

We offer a 30-day trial. If you’re not satisfied, return Cryo-1 for a full refund. Buyer pays return shipping. Device must ship back in original packaging.

Yes, you can find instructions on how to pay with your FSA/HSA card here.

Yes, Cryomedics products ship to most countries worldwide. Shipping costs and times vary by region.

Your pre-orders may be cancelled prior to January 15th, 2026 which is when we expect your order to ship. After that your order will be subject to our standard return and warranty policy.

Pre-ordered units are expected to ship from our U.S. warehouse in mid January 2026.

Pre-order customers lock significant discounts off the retail price. You will also receive priority delivery and free shipping.